tert-butyl (3E)-3-[(tetramethyl-1,3,2-dioxaborolan-2-yl)methylidene]piperidine-1-carboxylate
tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate
CAS: 2376764-47-3
Molecular Formula: C17H30BNO4
tert-butyl (3E)-3-[(tetramethyl-1,3,2-dioxaborolan-2-yl)methylidene]piperidine-1-carboxylate - Names and Identifiers
tert-butyl (3E)-3-[(tetramethyl-1,3,2-dioxaborolan-2-yl)methylidene]piperidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C17H30BNO4 |
| Molar Mass | 323.24 |
tert-butyl (3E)-3-[(tetramethyl-1,3,2-dioxaborolan-2-yl)methylidene]piperidine-1-carboxylate - Introduction
tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl) piperidine-1-carboxylate, also known as tert-butyl ester 3-((4,4,5, 5-Tetramethyl -1,3, 2-dioxabororan-2-yl) methylene)piperidine-1-carboxylate (tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate), is an organic compound.
Nature:
-Appearance: solid powder or crystalline substance.
-Solubility: Soluble in common organic solvents.
-Melting point: About 70-75 ℃.
Use:
- tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate are often used as intermediates in organic synthesis to construct complex organic molecular structures.
-In the field of medicine, it can be used to synthesize anti-tumor drugs, antiviral drugs and other drugs.
Method:
tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl) piperidine-1-carboxylate can be prepared by various methods, A common method is through a nucleophilic substitution reaction: first, 4,4,5,5-tetramethyl-1,3, the 2-dioxabororane and 3-amino-1-piperidinecarboxylate are reacted to give the methylated product, which is subsequently reacted with the tert-butyl ester by acylation to give the final product.
Safety Information:
- tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate need to pay attention to fire prevention and explosion prevention during use and storage.
-Avoid contact with skin, eyes and respiratory tract and wear appropriate personal protective equipment when using.
-It should be used in a well-ventilated place, away from open flames or high temperatures.
-in the use and handling process, pay attention to comply with the relevant safety procedures.
Nature:
-Appearance: solid powder or crystalline substance.
-Solubility: Soluble in common organic solvents.
-Melting point: About 70-75 ℃.
Use:
- tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate are often used as intermediates in organic synthesis to construct complex organic molecular structures.
-In the field of medicine, it can be used to synthesize anti-tumor drugs, antiviral drugs and other drugs.
Method:
tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl) piperidine-1-carboxylate can be prepared by various methods, A common method is through a nucleophilic substitution reaction: first, 4,4,5,5-tetramethyl-1,3, the 2-dioxabororane and 3-amino-1-piperidinecarboxylate are reacted to give the methylated product, which is subsequently reacted with the tert-butyl ester by acylation to give the final product.
Safety Information:
- tert-butyl 3-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methylene)piperidine-1-carboxylate need to pay attention to fire prevention and explosion prevention during use and storage.
-Avoid contact with skin, eyes and respiratory tract and wear appropriate personal protective equipment when using.
-It should be used in a well-ventilated place, away from open flames or high temperatures.
-in the use and handling process, pay attention to comply with the relevant safety procedures.
Last Update：2024-04-09 21:01:54
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